See this article. Some edited excerpts follow. See the article for much more detail.
"But once in a while, something goes wrong. In Buddhism this is known as
falling into 'the pit of the void.' Young is more modern: 'Psychiatrists
call it Depersonalization and De-realization Disorder, or DP/DR. I call
it Enlightenment’s evil twin. [...] If the very real benefits of mindfulness add up to the good-news mental
health story of our time, then, like so many good things, there is also a
shadowy seam, an experience known popularly as the Dark Night, after the writings of the famous Carmelite mystic St. John of the Cross. [...] The full range of symptoms, from mild to intense, include headaches,
panic, mania, confusion, hallucinations, body pain and pressure,
involuntary movements, the de-repression of emotionally-charged
psychological material, extreme fear and – perhaps the central feature –
the dissolution of the sense of self."
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