"Dividing the connectomes into four tiers based on degree magnitudes indicates that the most complex nodes are neither those with the highest nor lowest degrees but are instead found in the middle tiers. […] The most complex tier (Tier 3) involves regions believed to bridge high-order cognitive (Tier 1) and low-order sensorimotor processing (Tier 2)."
"The results show that hub nodes (Tier 1(t)) and peripheral nodes (Tier 4(b)) are contributing less to the greater complexity exhibited in the human brain connectome than middle tiers. In fact, this is particularly true of hub nodes."
Also note that "this concerns wholly separate considerations of topology to the well-known paradigms of small-world and scale-free complex networks."